Dynamic reprogramming of chromatin: paradigmatic palimpsests and HES factors
نویسندگان
چکیده
منابع مشابه
Dynamic reprogramming of chromatin: paradigmatic palimpsests and HES factors
Temporal and spatial control of transcription in development is dictated to a great extent by transcriptional repressors. Some repressor complexes, such as Polycomp-group proteins, induce relatively long-term non-permissive states, whereas others such as hairy/enhancer of split (HES) family repressors are linked to dynamically modulated chromatin states associated with cycling expression of tar...
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We usually think of palimpsests as old texts written on parchment over earlier erasures, but digital technology has caused the present to be the most palimpsestic of times. A survey of modern-day palimpsests leads to an examination of why and how people created palimpsests in the past. Unlike the old analog documents, our electronic palimpsested texts face the likelihood of relatively rapid to ...
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The pluripotent state of embryonic stem cells (ESCs) provides a unique perspective on regulatory programs that govern self-renewal and differentiation and somatic cell reprogramming. Here, we review the highly connected protein and transcriptional networks that maintain pluripotency and how they are intertwined with factors that affect chromatin structure and function. The complex interrelation...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2015
ISSN: 1664-8021
DOI: 10.3389/fgene.2015.00029